Fluid Replacement With Hydroxyethyl Starch in Critical Care
نویسندگان
چکیده
منابع مشابه
Fluid replacement with hydroxyethyl starch in critical care--a reassessment.
BACKGROUND Hydroxyethyl starch (HES) is used for fluid replacement in millions of patients around the world every year, yet it has been found to have adverse effects that have a negative impact on patient survival. Recent clinical trials with a modern HES solution (HES 130) and meta-analyses now enable a reassessment of its risks and benefits. METHODS On the basis of a selective literature se...
متن کاملHydroxyethyl starch or saline for fluid resuscitation in intensive care.
BACKGROUND The safety and efficacy of hydroxyethyl starch (HES) for fluid resuscitation have not been fully evaluated, and adverse effects of HES on survival and renal function have been reported. METHODS We randomly assigned 7000 patients who had been admitted to an intensive care unit (ICU) in a 1:1 ratio to receive either 6% HES with a molecular weight of 130 kD and a molar substitution ra...
متن کاملHydroxyethyl starch for fluid resuscitation in critically ill patients.
BACKGROUND Intravenous fluid therapy is one of the most frequent interventions provided to patients in the intensive care unit; however, the type of fluid (i.e., crystalloid or colloid) used for resuscitation remains controversial. The most common type of colloid administered to resuscitate critically ill patients is hydroxyethyl starch (HES); however, its safety and efficacy have not been rigo...
متن کاملHydroxyethyl starch in patients with trauma.
Editor—The Fluids in Resuscitation of Severe Trauma (FIRST) randomized trial conducted by James and colleagues compared hydroxyethyl starch (HES) 130/0.4 with 0.9% saline in the resuscitation of 115 patients with severe blunt or penetrating trauma at a single centre in South Africa. In blunt trauma, which accounts for 86–97% of all traumatic injuries in Europe, 3 no differences were found betwe...
متن کاملHemodynamic effects of volume replacement with saline solution and hypertonic hydroxyethyl starch in dogs.
PURPOSE To investigate hemodynamic response to volume replacement with saline solution and hypertonic hydroxyethyl starch in hypovolemic dogs. METHODS Forty dogs under general anesthesia and hemodynamic monitoring, following measurements at baseline, were bled 20 ml x Kg(-1) and parameters were measured again after 10 minutes. The animals were randomly divided in two groups and volume replace...
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ژورنال
عنوان ژورنال: Deutsches Aerzteblatt Online
سال: 2013
ISSN: 1866-0452
DOI: 10.3238/arztebl.2013.0443